Roger L. Jackson occupies a unique place in the hearts of horror and animation aficionados, largely due to his iconic vocal performances that have resonated across generations of physical media releases. For horror collectors, his most prized contribution is undoubtedly the chilling voice of Ghostface, the relentless killer in Wes Craven's seminal *Scream* franchise. From the original 1996 slasher classic, a VHS staple and later a widely collected Blu-ray, through subsequent sequels and the recent 4K UHD releases of *Scream* (2022) and *Scream VI* (2023), Jackson’s menacing whispers and taunting phone calls are central to the series' enduring appeal and are etched into the auditory terror of home video history. Beyond the meta-terror of Woodsboro, Jackson is equally celebrated in animation circles for his unforgettable portrayal of Mojo Jojo, the super-intelligent, verbose chimpanzee villain from Cartoon Network's beloved *The Powerpuff Girls*. His distinctive voice, capable of both maniacal grandiosity and comedic exasperation, has made Mojo Jojo a fan-favorite, gracing countless DVD box sets and collector's editions of the animated series. Collectors seek out Jackson's work not just for the character, but for the inherent quality of his vocally distinct performances, which elevate instantly recognizable cultural touchstones within their home media libraries.